DMCCB Basel Symposium 2022
«Intrinsically Disordered Proteins as Drug Targets»
January 31, 2022, online
Program
10.30
Welcome and Introduction
10.45
11.20
Ben Schuler, University of Zurich, CH
«Dynamics and interactions of IDPs from single-molecule spectroscopy»
«Dynamics and interactions of IDPs from single-molecule spectroscopy»
11.55
Lunch Break and virtual Poster Session
13.00
9 short communications (8min + 2min Q&A)
Aline Carrel, University of Bern, CH
«Exploring bicyclic diamines as drug scaffolds»
«Exploring bicyclic diamines as drug scaffolds»
Basilius Sauter , University of Basel, CH
«An assessment of the mutational load caused by various reactions used in DNA encoded libraries»
«An assessment of the mutational load caused by various reactions used in DNA encoded libraries»
Xingguang Cai , University of Bern, CH
«Stereorandomized peptide dendrimer from chemical space had reduced hemolysis and promoted antimicrobial potency»
«Stereorandomized peptide dendrimer from chemical space had reduced hemolysis and promoted antimicrobial potency»
Chiara Borsari , University of Basel, CH
«Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα»
«Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα»
Jonathan Hall , ETH Zurich, CH
«Using RNA PROTACs in a new approach to target RNA-Binding Proteins (RBPs)»
«Using RNA PROTACs in a new approach to target RNA-Binding Proteins (RBPs)»
Michael Assfalg , University of Verona, IT
«Conformational transitions of amyloidogenic proteins at nanoparticle surfaces»
«Conformational transitions of amyloidogenic proteins at nanoparticle surfaces»
Dilmehak Kaur , Indian Institute of Technology, Kharagpur
«Targeting Intrinsically Disordered Regions (IDRs) in Viral Proteins via Molecular Recognition Features (MoRF) Analysis»
«Targeting Intrinsically Disordered Regions (IDRs) in Viral Proteins via Molecular Recognition Features (MoRF) Analysis»
Jinming Wu , Paul Scherrer Institute, CH
«Cryo-electron Microscopy Imaging of Alzheimer's Amyloid-beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold»
«Cryo-electron Microscopy Imaging of Alzheimer's Amyloid-beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold»
Ivan Urosev , University of Basel & ETH Zurich, CH
«Phase Separation of Intrinsically Disordered Protein Polymers Mechanically Stiffens Fibrin Clots»
«Phase Separation of Intrinsically Disordered Protein Polymers Mechanically Stiffens Fibrin Clots»
14.40
Short Break
15.35
Sarah Slavoff, Yale University, US
«Dark Matter of the Human Genome»
«Dark Matter of the Human Genome»
16.10
Short Break
16.30
Dan Nomura, Berkeley, US
«Reimagining Druggability using Chemoproteomic Approaches»
17.05
Virginia Burger, New Equilibrium Biosciences, Cambridge, US
«Unlocking conformation-based drug discovery for IDPs»
17.40
Presentation prizes and closing remarks
18.00
End of the Symposium